Association between IRF6 SNPs and Oral Clefts in West China
نویسندگان
چکیده
منابع مشابه
Lack of association between IRF6 polymorphisms and nonsyndromic oral clefts in South Indian population
Objec ve: This present study is aimed to inves gate the associa on between interferon regulatory factor 6 (IRF6), single nucleo de polymorphisms (SNPs), and nonsyndromic cle lip without without cle palate (NSCLP) in the South Indian popula on. Subject and Methods: For this study, 190 unrelated NSCLP pa ents and 189 controls with‐ out cle s were genotyped with rs2235371 (V274...
متن کاملIRF6 AP-2a binding site promoter polymorphism is associated with oral clefts in Latvia.
OBJECTIVE To evaluate the association between AXIN2, CDH1 and IRF6 with oral clefts in a cohort from Latvia. MATERIAL AND METHODS 283 unrelated individuals, 93 born with isolated oral clefts and 190 individuals born without any structural abnormalities were evaluated. Cleft type and dental anomalies outside the cleft area were determined by clinical examination. Four SNPs were selected for th...
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Little information is available concerning the prevalence of caries among patients with oral clefts in Eastern China. Consecutive patients aged 6-18 with oral clefts were recruited. Patients were stratified into 2 groups according to their ages, namely Group I with aged 6-12 and Group II with aged 13-18. For each age group, the children were further divided into three subgroups according to the...
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Transforming growth factor alpha (TGFA) is a well-characterized mammalian growth factor. Since the first report of an association between DNA sequence variants at the TGFA genetic locus and nonsyndromic oral clefts, 47 studies have been carried out, producing conflicting results. In this review, the author synthesizes findings from published reports on the association between the TGFA gene and ...
متن کاملIs there a relationship between risk factors for oral clefts?
Oral clefts include cleft lip (CL), cleft palate (CP), and cleft lip and palate (CLP) and collectively these constitute a heterogeneous group of nonfatal birth defects known to be multifactorial in origin, in that both genes and environmental factors contribute to their etiology (Mitchell et al., ’02). The incidence of oral clefting varies from 0.6 to 1.7 per 1,000 Caucasian births. African Ame...
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ژورنال
عنوان ژورنال: Journal of Dental Research
سال: 2009
ISSN: 0022-0345,1544-0591
DOI: 10.1177/0022034509341040